|
KMID : 1812020170230030341
|
|
Journal of Neurogastroenterology and Motility
2017 Volume.23 No. 3 p.341 ~ p.348
|
|
|
Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal
|
|
|
|
|
Abstract
|
|
|
|
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for agents targeting histamine receptors as a potential therapeutic option in clinical treatment. In this review, the role of histamine and histamine receptors is debated. Moreover, the clinical evidence of anti-histamine therapeutics in irritable bowel syndrome is discussed.
|
|
|
KEYWORD
|
|
|
Ebastine, Irritable bowel syndrome, Mast cells, Receptors, histamine
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|